Development and Application of an In-house Line Probe Assay for Hepatitis C Virus Genotyping
نویسندگان
چکیده
منابع مشابه
development and application of an in-house line probe assay for hepatitis c virus genotyping
background hepatitis c virus (hcv) is the major cause of chronic liver disease. hcv is a single stranded positive sense rna of approximately 9.6 kb. because of high conservativeness of 5΄untranslated region of hcv genome, it is widely used for virus genotyping. different methods are used for the virus genotyping, but all involve some difficulties. objectives the aim of the present study was to ...
متن کاملDevelopment and Application of an In-house Line Probe Assay for Hepatitis C Virus Genotyping
BACKGROUND Hepatitis C virus (HCV) is the major cause of chronic liver disease. HCV is a single stranded positive sense RNA of approximately 9.6 Kb. Because of high conservativeness of 5΄untranslated region of HCV genome, it is widely used for virus genotyping. Different methods are used for the virus genotyping, but all involve some difficulties. OBJECTIVES The aim of the present study was t...
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Because of the enormous variability of hepatitis C virus (HCV), the development of reliable genotyping assays is a formidable challenge. The optimal genotyping region appears to be the 5' untranslated region (UR) because of high conservation within, but considerable variability between, genotypes. In this study, 21 probes dispersed over seven variable 5' UR areas were applied to a line probe as...
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15 صفحه اولUse of a commercially available line probe assay for genotyping of hepatitis C virus 5a strains.
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ژورنال
عنوان ژورنال: Hepatitis Monthly
سال: 2013
ISSN: 1735-143X,1735-3408
DOI: 10.5812/hepatmon.6767